Snake venom poisoning is an important medical problem. Toxicity estimations for different snake venoms or proteins, nonetheless, have been a major research activity of many investigators of the possible correlation of estimates with most of the economically important animal, as well as human mortality has probably been a prime factor. In this book, research conclusions were made to justify the comparative study of the deadly venomous species such as of elapidae and viperidae family, their toxicity levels on vital organs of the body. Similarly, the estimation of LD50 values of snake venoms of various species electrocardiographic characterization of snake venoms was studied. The results obtained would be helpful to clinical practitioners and researchers in the management of snakebite victims for precise and accurate diagnosis and treatment.